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Lyme disease
MONDO:0019632Lyme disease (named after the towns in the USA where the disease was first identified) is a bacterial infection caused by Borrelia burgdorferi.
Also known as: Borrelia, Borrelia burgdorferi infection, Borreliella burgdorferi caused disease or disorder, Borreliella burgdorferi disease or disorder, Borreliella burgdorferi infectious disease, Lyme borreliosis, Lyme disease
31 clinical trials for this condition and its sub-types, 30 tagged with Lyme disease itself.
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New mRNA vaccine could stop lyme disease in its tracks
Vaccine OngoingThis study tests an experimental mRNA vaccine (mRNA-1982) designed to prevent Lyme disease, which is spread by tick bites. About 350 healthy adults aged 18 to 70 will receive either the vaccine or a placebo to check for safety and immune response. The goal is to find the best dos…
Phase 2 • Sponsor: ModernaTX, Inc. • Aim: Vaccine
Last updated Aug 05, 2026 00:00 UTC
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Promising lyme vaccine moves to final testing phase
Vaccine OngoingThis study tests a new Lyme disease vaccine (VLA15) in about 200 healthy adults aged 18 to 44. Participants receive five shots over two years—four of the vaccine and one of salt water—to see if different timing schedules are safe and produce a strong immune response. The goal is …
Phase 3 • Sponsor: Pfizer • Aim: Vaccine
Last updated Jun 27, 2026 12:29 UTC
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Can telemedicine bring IV antibiotics home?
Disease control OngoingThis trial tests a new model where patients with infections receive intravenous antibiotics at home instead of staying in the hospital. Nurses from a municipal response team visit the patient, while hospital doctors oversee the treatment remotely using telemedicine and welfare te…
Sponsor: Helse Møre og Romsdal HF • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Could a single pill stop lyme disease before it starts?
Prevention OngoingThis study tests a new pill called TP-05 (lotilaner) to see if it can prevent Lyme disease in healthy adults who are often around ticks. The pill is already used in pets to kill ticks. Researchers will give either a low dose, high dose, or placebo to 700 volunteers and watch for …
Phase 2 • Sponsor: Tarsus Pharmaceuticals, Inc. • Aim: Prevention
Last updated Jul 11, 2026 00:00 UTC