Lyme disease
MONDO:0019632Lyme disease (named after the towns in the USA where the disease was first identified) is a bacterial infection caused by Borrelia burgdorferi.
Also known as: Borrelia, Borrelia burgdorferi infection, Borreliella burgdorferi caused disease or disorder, Borreliella burgdorferi disease or disorder, Borreliella burgdorferi infectious disease, Lyme borreliosis, Lyme disease
31 clinical trials for this condition and its sub-types, 30 tagged with Lyme disease itself.
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Could a malaria drug ease lingering lyme symptoms?
Symptom relief Not yet recruitingThis study tests whether adding hydroxychloroquine (a malaria drug) to standard doxycycline treatment can reduce long-term complaints in adults with Lyme disease. Fifty participants will take either hydroxychloroquine or a placebo twice daily for 28 days, with follow-up visits ov…
Phase 4 • Sponsor: Radboud University Medical Center • Aim: Symptom relief
Last updated Aug 29, 2026 00:00 UTC
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Immune cell tracking could sharpen lyme disease diagnosis
Knowledge-focused Not yet recruitingThis study explores a new way to diagnose Lyme disease by measuring immune cell responses to the bacteria. Researchers use a technique called flow cytometry to analyze T-cells from patients with a late-stage form of Lyme disease. The goal is to see if this method can tell active …
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Hidden Tick-Borne arthritis under investigation in denmark
Knowledge-focused Not yet recruitingThis study aims to find out how common Borrelia arthritis is in Denmark and how it affects patients. Researchers will test blood and joint fluid from 350 adults with joint swelling to look for Borrelia bacteria. Participants will also answer questions about symptoms and tick expo…
Sponsor: Fredrikke Christie Knudtzen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC