Leukocyte adhesion deficiency

MONDO:0017570

Leukocyte adhesion deficiency (LAD) is a primary immunodeficiency characterized by defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections.

Also known as: LAD

7 clinical trials for this condition and its sub-types, 3 tagged with Leukocyte adhesion deficiency itself.

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Where it sits in the disease tree

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Part of

↑ Autosomal recessive disease (994) ↑ Functional neutrophil defect (13)

Sub-types of Leukocyte adhesion deficiency

Leukocyte adhesion deficiency 1 7 trials
Leukocyte adhesion deficiency type II 2 trials
Leukocyte adhesion deficiency 3 0 trials

Including sub-types (7) Tagged with Leukocyte adhesion deficiency (3)

Trials to join now! 2 Not yet finished but already full! 1

Gene therapy for rare immune disease shows promise in Long-Term study

Disease control Ongoing

This study follows 9 people with a rare immune disorder called LAD-I who received a one-time gene therapy that adds a working copy of the ITGB2 gene to their own blood stem cells. Researchers want to see if the treatment safely controls the disease over many years and helps patie…

Sponsor: Rocket Pharmaceuticals Inc. • Aim: Disease control

Last updated Jun 27, 2026 08:05 UTC

Leukocyte adhesion deficiency

Where it sits in the disease tree

Gene therapy for rare immune disease shows promise in Long-Term study