Letterer-Siwe disease

A multifocal, multisystem form of Langerhans-cell histiocytosis. There is involvement of multiple organ systems including the bones, skin, liver, spleen, and lymph nodes. Patients are usually infants presenting with fever, hepatosplenomegaly, lymphadenopathy, bone and skin lesions, and pancytopenia.

Also known as: acute and disseminated Langerhans cell histiocytosis, acute disseminated Langerhans cell histiocytosis, letterer-Siwe disease, multifocal multisystem Langerhans cell histiocytosis, L-S disease, histiocytosis X, acute disseminated

1849 clinical trials for this condition and its sub-types, 0 tagged with Letterer-Siwe disease itself.