Leptomeningeal melanoma

MONDO:0003761

A melanoma that arises from leptomeningeal melanocytes.

Also known as: leptomeningeal melanoma, leptomeninx melanoma, leptomeninx melanoma (disease), malignant melanoma of meninges, melanoma (disease) of leptomeninx, melanoma of the leptomeninges, meningeal melanoma, melanoma of leptomeninges

2779 clinical trials for this condition and its sub-types, 1 tagged with Leptomeningeal melanoma itself.

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Where it sits in the disease tree

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Part of

↑ Malignant leptomeningeal tumor (4) ↑ Primary melanoma of the central nervous system (3)

Sub-types of Leptomeningeal melanoma

Adult leptomeningeal melanoma 0 trials
Pediatric leptomeningeal melanoma 0 trials

Including sub-types (2779) Tagged with Leptomeningeal melanoma (1)

Not yet recruiting 1

Immune cells injected into spine to fight brain cancer

Disease control Not yet recruiting

This early-phase trial tests whether immune cells (CD8+ T cells) given through a spinal tap are safe for people with melanoma that has spread to the lining of the brain. Only 8 participants will receive the treatment. The main goal is to check for side effects, not to cure the di…

Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Aug 14, 2026 00:00 UTC

Leptomeningeal melanoma

Where it sits in the disease tree

Immune cells injected into spine to fight brain cancer