Lentigo maligna melanoma
MONDO:0023619A skin cancer that usually develops in older, fair-skinned adults. The average age of diagnosis is 65. LMM is thought to be caused by a history of sun exposure to the affected area. Treatment includes surgery to remove as much of the LMM as possible.
Also known as: lentigo maligna melanoma, malignant lentigo melanoma, Hutchison melanotic freckle, LMM, SKLMM
2771 clinical trials for this condition and its sub-types, 4 tagged with Lentigo maligna melanoma itself.
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Can a skin cream shrink facial melanoma before surgery?
Disease control CompletedLentigo maligna is an early form of melanoma that appears on sun-exposed skin, often on the face. Doctors usually remove it with surgery, but it can be hard to decide how much tissue to take. This trial tests whether applying imiquimod cream for four weeks before surgery can shri…
Phase 3 • Sponsor: Nantes University Hospital • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Could a gel replace surgery for face melanoma?
Disease control CompletedThis study tested a gel called Picato (ingenol mebutate) on 20 people with a very early form of melanoma on the face, called lentigo maligna. Participants applied the gel once a day for three days. The goal was to see if the gel could make the cancer disappear completely, offerin…
Phase 2 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC