Lassa fever
MONDO:0005820A viral hemorrhagic fever that is caused by the Lassa virus, which is transmitted by contact with infected rodents; it is characterized by fever, headache, malaise, myalgia, and hearing loss.
Also known as: LF, Lassa hemorrhagic fever
9 clinical trials for this condition and its sub-types, 6 tagged with Lassa fever itself.
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New vaccine could stop deadly lassa fever
Vaccine OngoingThis early-stage trial is testing a new vaccine called LASSARAB, designed to protect against Lassa fever, a serious viral illness. The vaccine uses a modified rabies virus to deliver the Lassa antigen and includes an adjuvant to boost the immune response. 55 healthy adults will r…
Phase 1 • Sponsor: Wilbur Chen, MD, MS • Aim: Vaccine
Last updated Jun 27, 2026 13:00 UTC
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Experimental IV drug targets deadly fevers in military personnel
Disease control PausedThis trial investigates whether intravenous ribavirin can help treat people with Crimean-Congo hemorrhagic fever or Lassa fever, two severe viral infections. The study enrolls up to 30 military-affiliated adults who have a probable or suspected case. Participants receive a specif…
Sponsor: U.S. Army Medical Research and Development Command • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New oral drug shows promise against deadly lassa fever in west africa trial
Disease control PausedThis study tests a new oral antiviral drug, ARN-75039, for treating Lassa fever, a serious viral illness common in West Africa. About 135 hospitalized adults will receive either a high or low dose of the new drug or the standard IV treatment, ribavirin, for 10 days. The goal is t…
Phase 2 • Sponsor: Arisan Therapeutics, Inc. • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC