KSHV inflammatory cytokine syndrome
MONDO:0023528A syndrome caused by Kaposi sarcoma-associated herpesvirus (KSHV) infection. It manifests with fever, weight loss, and fluid retention in the legs or abdomen. Patients are at risk of developing KSHV-related cancers including Kaposi sarcoma and lymphoma.
Also known as: KICS, KSHV inflammatory cytokine syndrome, Kaposi-sarcoma associated Herpesvirus (KSHV) inflammatory cytokine syndrome
6 clinical trials for this condition and its sub-types, 4 tagged with KSHV inflammatory cytokine syndrome itself.
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New study targets rare Virus-Driven inflammatory syndrome
Disease control Recruiting nowThis study looks at a newly recognized disease called KSHV Inflammatory Cytokine Syndrome (KICS), caused by a virus that can also lead to certain cancers. Researchers aim to learn more about the disease and test experimental treatments, including antiviral and chemotherapy drugs,…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New drug trial targets deadly inflammation in HIV patients
Disease control Recruiting nowThis study tests a drug called pacritinib in people with HIV who have two rare conditions caused by the Kaposi sarcoma herpesvirus (KSHV): KSHV-associated multicentric Castleman disease (MCD) and KSHV inflammatory cytokine syndrome (KICS). These conditions cause severe, life-thre…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC