Kawasaki disease
MONDO:0012727A rare inflammatory disease characterized by an acute febrile, systemic, self-limiting, medium-vessel vasculitis primarily affecting children. It often causes acute coronary arteritis which is associated with coronary arterial aneurysms (CAA) that may be life threatening when untreated.
Also known as: Kawasaki syndrome, acute febrile mucocutaneous lymph node syndrome, acute febrile mucocutaneous lymph node syndrome [MCLS], infantile polyarteritis nodosa, mucocutaneous lymph node syndrome
17 clinical trials for this condition and its sub-types, 15 tagged with Kawasaki disease itself.
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Heart-Saving combo: steroid plus standard therapy may shield kids from kawasaki damage
Disease control CompletedThis study looked at whether adding a steroid called prednisolone to the usual treatment (immunoglobulin and aspirin) could reduce heart artery damage in children with Kawasaki disease. Over 3,200 children took part. The goal was to see if the combination therapy lowers the chanc…
Phase 3 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New combo therapy aims to stop heart damage in kids with kawasaki disease
Disease control CompletedThis early-phase study tested a combination of atorvastatin and anakinra in 5 children with Kawasaki disease who had coronary artery abnormalities. The goal was to see if these drugs could safely reduce artery inflammation and prevent future heart problems. The study focused on s…
Early phase 1 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New hope for kids with stubborn kawasaki disease: drug targets fever and heart risks
Disease control CompletedThis study tested a drug called TA-650 in 31 children with Kawasaki disease whose fever did not go away after standard IVIG treatment. The goal was to see if TA-650 could bring down the fever faster and prevent damage to heart arteries compared to another immunoglobulin treatment…
Phase 3 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Kawasaki Kids' hearts under the microscope 5 years later
Knowledge-focused CompletedThis study looked at the heart health of 61 children who had Kawasaki disease 5 years earlier and were treated with IVIG. Researchers compared them to healthy children using blood tests, blood pressure, artery stiffness, and heart imaging. The goal was to find early signs of hear…
Sponsor: Medical University of Warsaw • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC