Kawasaki disease
MONDO:0012727A rare inflammatory disease characterized by an acute febrile, systemic, self-limiting, medium-vessel vasculitis primarily affecting children. It often causes acute coronary arteritis which is associated with coronary arterial aneurysms (CAA) that may be life threatening when untreated.
Also known as: Kawasaki syndrome, acute febrile mucocutaneous lymph node syndrome, acute febrile mucocutaneous lymph node syndrome [MCLS], infantile polyarteritis nodosa, mucocutaneous lymph node syndrome
17 clinical trials for this condition and its sub-types, 15 tagged with Kawasaki disease itself.
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Could a once-daily pill replace warfarin for kids with rare heart aneurysms?
Disease control Recruiting nowThis trial compares two blood thinners—rivaroxaban (Xarelto) and warfarin—in children over 2 years old who have giant coronary artery aneurysms caused by Kawasaki disease. The goal is to see if rivaroxaban is safer and as effective as warfarin at preventing blood clots, major ble…
Phase 4 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Could a cholesterol drug help Kids' hearts after kawasaki disease?
Disease control Recruiting nowThis phase 3 trial is testing whether atorvastatin, a common cholesterol drug, is safe and can reduce inflammation in children with Kawasaki disease who also have coronary artery abnormalities. The study will enroll 9 children and give them different doses of atorvastatin for 6 w…
Phase 3 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a blood thinner protect Kids' hearts after kawasaki? small study aims to find out
Disease control Recruiting nowThis pilot study tests the blood thinner Rivaroxaban in 10 Chinese children who developed giant coronary artery aneurysms after Kawasaki disease. The goal is to see if a specially adjusted dose can prevent new blood clots in the heart arteries while keeping bleeding risks low. Ch…
Phase 4 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jun 26, 2026 14:36 UTC
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AI tool aims to speed up kawasaki disease diagnosis in kids
Diagnosis Recruiting nowThis study is testing a computer tool called Kawasaki MATCH that helps doctors decide if a child with fever has Kawasaki Disease. The tool uses patient age, lab results, and symptoms to give a risk score. Researchers want to see if using this tool leads to faster treatment. About…
Sponsor: University of California, San Diego • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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Massive study aims to crack the code on Kids' medications
Knowledge-focused Recruiting nowThis study is collecting blood and other samples from 5,000 children and young adults (under 21) who are already taking certain medications as part of their regular care. The goal is to understand how these drugs move through and affect children's bodies, so doctors can prescribe…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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Can a simple score predict which kids with kawasaki disease need stronger treatment?
Knowledge-focused Recruiting nowThis study looks at two scoring tools (Kobayashi and Kawanet) to see if they can identify children with Kawasaki disease who are likely to resist standard IVIG treatment. About 10-20% of children don't respond to IVIG and face a higher risk of heart problems. Researchers will enr…
Sponsor: Meyer Children's Hospital IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC