Juvenile hyaline fibromatosis

MONDO:0016071

Juvenile hyaline fibromatosis (JHF) is a rare soft tissue tumor, characterized by papulo-nodular skin lesions (especially around the head and neck), soft tissue masses, gingival hypertrophy, joint contractures, and osteolytic bone lesions in variable degrees. Joint contractures may cripple patients and delay normal motor development if occurring in infancy. Severe gingival hyperplasia can interfere with eating and delay dentition. Histopathology analysis of involved tissues reveals cords of spindle-shaped cells embedded in an amorphous, hyaline material. JHF is a mild form of infantile systemic hyalinosis.

Also known as: Molluscum fibrosum, Murray-Puretic-Drescher syndrome, Puretic syndrome, mesenchymal dysplasia

1449 clinical trials for this condition and its sub-types, 0 tagged with Juvenile hyaline fibromatosis itself.

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↑ Bone neoplasm (2118) ↑ Hereditary disorder of connective tissue (1314) ↑ Hereditary skin disorder (885) ↑ Soft tissue neoplasm (741) ↑ Dermis tumor (90) ↑ Hyaline fibromatosis syndrome (2)

Including sub-types (1449) Tagged with Juvenile hyaline fibromatosis (0)

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