Joint laxity, familial
MONDO:0007842A type of Ehlers-Danlos syndrome characterized by generalized joint hypermobility often complicated by dislocation of major joints, particularly the shoulder but in some cases the kneecap. Congenital hip dislocation has also been frequently reported. The syndrome has been described in several families. It is transmitted as an autosomal dominant trait, with high penetrance.
Also known as: EDS XI, Ehlers-Danlos syndrome type 11, formerly, Joint instability syndrome, familial joint instability syndrome, familial joint laxity, joint laxity, familial, EDS 11 (formerly), EDS Xi
14 clinical trials for this condition and its sub-types, 14 tagged with Joint laxity, familial itself.
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Step-by-Step injections aim to ease chronic pain in Loose-Joint conditions
Disease control Not yet recruitingThis study tests a stepwise injection plan for adults with joint hypermobility and instability who haven't improved enough with physical therapy. The first step uses dextrose prolotherapy to stimulate healing in ligaments. If that doesn't reduce pain by at least 40%, participants…
Phase 1/2 • Sponsor: Manhattan Pain Medicine, PLLC • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Brain training boosts shoulder rehab? new trial investigates
Disease control Not yet recruitingThis study tests whether adding brain-challenging exercises (like reacting to lights while moving) to standard physical therapy helps people recover better after shoulder stabilization surgery. Thirty-two adults who had surgery for shoulder instability will be randomly assigned t…
Sponsor: Hacettepe University • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC