Ischemia reperfusion injury
MONDO:0005203Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (reperfusion), including swelling; hemorrhage; necrosis; and damage from free radicals. The most common instance is myocardial reperfusion injury.
142 clinical trials for this condition and its sub-types, 50 tagged with Ischemia reperfusion injury itself.
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Can a common supplement shield the heart from reperfusion injury?
Disease control OngoingThis trial tests whether L-carnitine, a natural compound, can reduce the damage that occurs when blood flow is restored to the heart after a heart attack. Researchers will give L-carnitine to patients with ST-elevation myocardial infarction (STEMI) who undergo angioplasty, and me…
Phase 2 • Sponsor: Ain Shams University • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Could estrogen shield transplanted kidneys?
Disease control OngoingThis study tests whether giving estrogen through a vein during kidney transplant surgery can reduce damage to the new kidney. It includes 30 women who need dialysis and are getting a kidney from a deceased donor. The goal is to see if estrogen helps the kidney work better right a…
Phase 1/2 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC