Intravascular large B-cell lymphoma

Intravascular large B-cell lymphoma (IVLBCL) is a very rare form of diffuse large B-cell lymphoma characterized by the selective growth of lymphoma cells within the lumina of small blood vessels (especially the capillaries) that most often presents with a wide range of clinical manifestations (as potentially any tissue can be involved), with patients from Western countries more frequently manifesting with neurological and cutaneous symptoms while patients from Asian countries more frequently displaying hepatosplenomegaly and thrombocytopenia. IVLBCL is characterized by an absence of lymphadenopathy, an aggressive clinical course and a poor prognosis.

Also known as: Tappeiner-Pfleger disease, angioendotheliomatosis proliferans systemisata, angiotropic large cell lymphoma, angiotropic lymphoma, intravascular B-cell lymphoma, intravascular large B-cell lymphoma, intravascular lymphomatosis, malignant angioendotheliomatosis

1995 clinical trials for this condition and its sub-types, 4 tagged with Intravascular large B-cell lymphoma itself.