Intracranial vasospasm
MONDO:0006812Constriction of arteries in the skull due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and brain ischemia that may lead to hypoxic-ischemic brain injury (hypoxia-ischemia, brain).
23 clinical trials for this condition and its sub-types, 13 tagged with Intracranial vasospasm itself.
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Back-Drain drug may stop brain artery spasms after aneurysm rupture
Prevention Not yet recruitingThis study tests whether giving a calcium channel blocker (nicardipine) through a lumbar drain can prevent dangerous artery spasms and delayed brain damage in people who have had a brain bleed from a ruptured aneurysm. About 214 adults with mild to moderate bleeds will receive th…
Phase 4 • Sponsor: Wake Forest University Health Sciences • Aim: Prevention
Last updated Aug 01, 2026 00:00 UTC
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Could a nerve block or ear stimulation prevent brain damage after a hemorrhage?
Knowledge-focused Not yet recruitingThis study looks at 300 adults with a brain bleed from a ruptured aneurysm. It tests a non-invasive headband to monitor brain blood flow and two nerve treatments (a neck injection and ear stimulation) to see if they improve brain function. The goal is to find better ways to preve…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC