Intermittent explosive disorder
MONDO:0001521A disorder characterized by recurrent episodes of serious assaultive acts or destruction of property due to a failure to resist aggressive impulses; the degree of aggression during these episodes is grossly out of proportion to any psychosocial provocation. The aggressive episodes are not etiologically linked to another mental disorder, a general medical condition, or substance use.
5 clinical trials for this condition and its sub-types, 4 tagged with Intermittent explosive disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
-
Scientists inject aggressive individuals with endotoxin to uncover Inflammation's role in anger
Knowledge-focused Recruiting nowThis study investigates whether inflammation worsens anger and aggression in people with Intermittent Explosive Disorder (IED). Researchers will give 112 participants (half with IED, half healthy controls) a low dose of endotoxin or a placebo on separate days. They will measure a…
Phase 2 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
-
Memory aid could unlock hidden mental health history
Knowledge-focused Recruiting nowThis study tests whether using a life history calendar—a simple grid that helps people recall important life events—can improve the accuracy of mental health surveys. Researchers in Hong Kong will ask 2,500 adults about their mental health using either a standard interview or one…
Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
-
Brain zaps may supercharge emotion control therapy
Knowledge-focused Recruiting nowThis study tests whether combining a one-time session of brain stimulation (rTMS or electrical scalp stimulation) with emotion regulation training helps people with mood, anxiety, or related disorders better control their emotions. 240 participants will learn either cognitive res…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC