Infantile spasms
MONDO:0018097A rare epilepsy syndrome characterized by onset of epileptic spasms in infants between 2 and 12 months of age, and rarely up to 24 months. Infants may have no antecedent history, or a history reflecting the underlying cause. The classical triad of epileptic spasms, hypsarrhythmia and developmental stagnation or regression is historically referred to as West syndrome.
Also known as: IESS, West syndrome, West's syndrome, infantile epileptic spasms syndrome, infantile spasms, infantile spasms syndrome, intellectual disability-hypsarrhythmia syndrome, X-linked infantile spasm syndrome
26 clinical trials for this condition and its sub-types, 8 tagged with Infantile spasms itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Infantile spasms
-
Could a Weight-Loss drug stop seizures in babies?
Disease control Recruiting nowThis study tests the drug fenfluramine in 10 children aged 12 to 36 months whose infantile spasms did not get better with standard treatments. The children take fenfluramine for 21 days, and doctors check brain waves and seizure diaries to see if the spasms stop. If it helps, the…
Phase 2 • Sponsor: Children's Hospital of Orange County • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
-
High-Fat diet may stop infant seizures before they start
Prevention Recruiting nowThis early-phase study tests whether a ketogenic (high-fat) diet can prevent epileptic spasms in infants with genetic epilepsy. Ten babies under 9 months old will receive the diet and be monitored with regular EEGs. The goal is to see if this approach is safe and feasible, potent…
Phase 1 • Sponsor: Heather Olson • Aim: Prevention
Last updated Jul 08, 2026 00:00 UTC
-
Scientists track 1,000 kids with rare epilepsies to uncover better treatments
Knowledge-focused Recruiting nowThis study follows 1,000 children and teens with rare epilepsies (like West and Dravet syndromes) to see how different treatments affect their seizures and thinking skills. Researchers will compare care across hospitals to find what works best. The goal is to give families cleare…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC