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Infant-type hemispheric glioma

MONDO:0858940

A malignant astrocytoma that is characterized by receptor tyrosine kinase fusions in the NTRK family, ROS1, ALK, or MET genes, that arises in the cerebral hemisphere and occurs in early childhood.

1449 clinical trials for this condition and its sub-types, 1 tagged with Infant-type hemispheric glioma itself.

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Where it sits in the disease tree

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Part of

↑ Astrocytic tumor (706)

Including sub-types (1449) Tagged with Infant-type hemispheric glioma (1)

Trials to join now! 1

Targeted drug lorlatinib tested in kids with rare brain tumors

Disease control Recruiting now

This early-phase study tests the drug lorlatinib in children and young adults (ages 1 to 21) with newly diagnosed high-grade glioma, a fast-growing brain tumor, that has a specific genetic change (ALK or ROS1 fusion). The goal is to see if the drug can shrink or control the tumor…

Early phase 1 • Sponsor: Nationwide Children's Hospital • Aim: Disease control

Last updated Jul 01, 2026 00:00 UTC