Inborn error of immunity
MONDO:0003778A disorder in which the immune system is unable to mount an adequate immune response.
Also known as: IEI, inborn errors of immunity, primary immunodeficiency disease, antibody deficiency syndrome, antibody deficiency syndromes, deficiency syndrome, antibody, deficiency syndrome, immunologic, deficiency syndrome, immunological
345 clinical trials for this condition and its sub-types, 121 tagged with Inborn error of immunity itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Inborn error of immunity
-
Lymphoproliferative syndrome 70 trials · 100 incl. sub-types
8 sub-types
- Castleman disease 8 trials · 18 incl. sub-types Sub-types →
- Autoimmune lymphoproliferative syndrome 11 trials · 12 incl. sub-types Sub-types →
- X-linked lymphoproliferative syndrome 7 trials · 11 incl. sub-types Sub-types →
- Dianzani autoimmune lymphoproliferative disease 0 trials
- Atypical lymphoproliferative disorder 0 trials
- Lymphoproliferative syndrome 1 0 trials
- Lymphoproliferative syndrome 2 0 trials
- Severe combined immunodeficiency due to CD70 deficiency 0 trials
-
B cell deficiency 5 trials · 86 incl. sub-types
5 sub-types
- Agammaglobulinemia 16 trials · 52 incl. sub-types Sub-types →
- Hyperimmunoglobulin syndrome 0 trials · 34 incl. sub-types Sub-types →
- Selective immunoglobulin deficiency disease 1 trial · 4 incl. sub-types Sub-types →
- PAX5-related B lymphopenia and autism spectrum disorder 0 trials
- Immunoglobulin beta deficiency 0 trials
-
Phagocyte bactericidal dysfunction 0 trials · 37 incl. sub-types
1 sub-type
- Chronic granulomatous disease 37 trials Sub-types →
-
Complement deficiency 2 trials · 28 incl. sub-types
8 sub-types
- Atypical hemolytic-uremic syndrome 19 trials Sub-types →
- Classic complement early component deficiency 0 trials · 7 incl. sub-types Sub-types →
- Disorder of lectin complement activation pathway 0 trials · 1 incl. sub-types Sub-types →
- Complement factor I deficiency 0 trials
- Complement receptor deficiency 0 trials
- Immunodeficiency due to a classical component pathway complement deficiency 0 trials Sub-types →
- Immunodeficiency due to a late component of complement deficiency 0 trials Sub-types →
- Recurrent Neisseria infections due to factor D deficiency 0 trials
-
Hereditary hemophagocytic lymphohistiocytosis 8 trials · 16 incl. sub-types
11 sub-types
- Chediak-Higashi syndrome 9 trials
- Griscelli syndrome type 2 1 trial
- Familial hemophagocytic lymphohistiocytosis 3 1 trial
- Hermansky-Pudlak syndrome 2 0 trials
- Hermansky-Pudlak syndrome 9 0 trials
- Familial hemophagocytic lymphohistiocytosis 2 0 trials
- Familial hemophagocytic lymphohistiocytosis 4 0 trials
- Familial hemophagocytic lymphohistiocytosis 5 0 trials
- Familial hemophagocytic lymphohistiocytosis type 1 0 trials
- Hemophagocytic lymphohistiocytosis due to RhoG deficiency 0 trials
- Hemophagocytic lymphohistiocytosis, familial, 6 0 trials
-
Aicardi-Goutieres syndrome 9 trials
10 sub-types
- Aicardi-Goutieres syndrome 1 2 trials Sub-types →
- Aicardi-Goutieres syndrome 2 0 trials
- Aicardi-Goutieres syndrome 3 0 trials
- Aicardi-Goutieres syndrome 4 0 trials
- Aicardi-Goutieres syndrome 5 0 trials
- Aicardi-Goutieres syndrome 6 0 trials
- Aicardi-Goutieres syndrome 7 0 trials
- Aicardi-Goutieres syndrome 8 0 trials
- Aicardi-Goutieres syndrome 9 0 trials
- Basal ganglia calcification, idiopathic, childhood-onset 0 trials
-
Chronic mucocutaneous candidiasis 4 trials
12 sub-types
- Autoimmune enteropathy and endocrinopathy - susceptibility to chronic infections syndrome 0 trials
- Candidiasis, familial, 1 0 trials
- Candidiasis, familial, 3 0 trials
- Candidiasis, familial, 4 0 trials
- Candidiasis, familial, 6 0 trials
- Candidiasis, familial, 8 0 trials
- Candidiasis, familial, 9 0 trials
- Chronic mucocutaneous candidiasis due to inhibition of lymphoblastic transformation 0 trials
- Chronic mucocutaneous candidiasis due to intrinsic defect in lymphoblastic transformation 0 trials
- Chronic mucocutaneous candidiasis due to lymphokine deficiency 0 trials
- Chronic mucocutaneous candidiasis due to monocyte chemotactic disorder 0 trials
- Immunodeficiency 51 0 trials
-
Immunoglobulin heavy chain deficiency 0 trials · 2 incl. sub-types
1 sub-type
- Selective IgG subclass deficiency 2 trials
-
A20 haploinsufficiency 1 trial
-
BENTA disease 1 trial
-
Immuno-osseous dysplasia 0 trials · 1 incl. sub-types
-
2 sub-types
- Inflammatory bowel disease 25 0 trials
- Inflammatory bowel disease 28 0 trials
-
NK cell deficiency 0 trials
-
Say-Barber-Miller syndrome 0 trials
-
T cell and NK cell immunodeficiency 0 trials
-
X-linked immunoneurologic disorder 0 trials
-
Dendritic cell deficiency 0 trials
-
2 sub-types
-
Immunodeficiency 28 0 trials
-
Immunodeficiency 33 0 trials
-
Immunodeficiency 37 0 trials
1 sub-type
-
Immunodeficiency 39 0 trials
-
Immunodeficiency 47 0 trials
-
Immunodeficiency 49 0 trials
-
Properdin deficiency, X-linked 0 trials
-
Trichohepatoenteric syndrome 0 trials
2 sub-types
- Trichohepatoenteric syndrome 1 0 trials
- Trichohepatoenteric syndrome 2 0 trials
Most studied deeper sub-types
Common variable immunodeficiency
(29)
Netherton syndrome
(16)
Multicentric Castleman disease
(13)
Granulomatous disease, chronic, X-linked
(10)
Hyper-IgM syndrome
(8)
Syndromic agammaglobulinemia
(7)
Combined immunodeficiency due to DOCK8 deficiency
(6)
Immunodeficiency 14
(6)
Activated PI3K-delta syndrome
(5)
C1 inhibitor deficiency
(5)
Hyper-IgE syndrome
(5)
Bruton-type agammaglobulinemia
(4)
X-linked lymphoproliferative disease due to XIAP deficiency
(4)
Autoimmune lymphoproliferative syndrome type 4
(3)
Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 1
(3)
Hyper-IgE recurrent infection syndrome 1, autosomal dominant
(3)
Hyper-IgM syndrome type 1
(3)
Idiopathic multicentric Castleman disease
(3)
Complement component 3 deficiency
(2)
FAS-related autoimmune lymphoproliferative syndrome
(2)