Immunotactoid glomerulopathy

MONDO:0019991

Immunotactoid glomerulopathy (ITG) is a very rare condition characterized by glomerular accumulation of microtubules in the mesangium and the glomerular basement membrane, that mainly presents with proteinuria, micro-hematuria, nephrotic syndrome, renal insufficiency and hematologic malignancy. ITG and non-amyloid fibrillary glomerulopathy (non-amyloid FGP) are often grouped together as pathogenetically related diseases.

Also known as: FGN, Immunotactoid glomerulonephritis, fibrillary glomerulonephritis

4 clinical trials for this condition and its sub-types, 1 tagged with Immunotactoid glomerulopathy itself.

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Where it sits in the disease tree

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↑ Glomerulonephritis (456) ↑ Immunotactoid or fibrillary glomerulopathy (1)

Including sub-types (4) Tagged with Immunotactoid glomerulopathy (1)

Trials to join now! 1

Hope for rare kidney disease: drug trial targets protein leak

Disease control Recruiting now

This study tests whether obinutuzumab, a drug used for certain blood cancers, can help people with fibrillary glomerulonephritis (FGN), a rare kidney condition that causes protein leakage and can lead to kidney failure. Twenty adults with confirmed FGN will receive the drug intra…

Phase 2 • Sponsor: Mayo Clinic • Aim: Disease control

Last updated Jun 27, 2026 12:06 UTC

Immunotactoid glomerulopathy

Where it sits in the disease tree

Hope for rare kidney disease: drug trial targets protein leak