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Idiopathic mast cell activation syndrome

MONDO:0100051

Mast cell activation syndrome where neither an allergy or other underlying disease is association, nor KIT-mutated mast cells are detectable.

Also known as: idiopathic MACS

2 clinical trials for this condition and its sub-types, 1 tagged with Idiopathic mast cell activation syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Idiopathic disease (1285) ↑ Mast cell activation syndrome (9)

Including sub-types (2) Tagged with Idiopathic mast cell activation syndrome (1)

Pain relief drug trial for mast cell syndrome stalls early

Symptom relief Stopped early

This Phase 2 trial tested whether FSD201 tablets could reduce chronic pain in adults with mast cell activation syndrome. The study planned to enroll many participants but was terminated early with only 2 people. No results are available to show if the drug works or is safe.

Phase 2 • Sponsor: Quantum Biopharma • Aim: Symptom relief

Last updated Jun 27, 2026 12:23 UTC