Idiopathic malabsorption due to bile acid synthesis defects

MONDO:0019393

Idiopathic malabsorption due to increased acid bile synthesis is an intestinal disease of unknown etiology characterized by an overproduction of bile acids which leads to chronic watery diarrhea.

Also known as: idiopathic bile acid malabsorption

6 clinical trials for this condition and its sub-types, 4 tagged with Idiopathic malabsorption due to bile acid synthesis defects itself.

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Where it sits in the disease tree

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Part of

↑ Idiopathic disease (1285) ↑ Malabsorption syndrome (120) ↑ Inborn disorder of bile acid synthesis (12)

Including sub-types (6) Tagged with Idiopathic malabsorption due to bile acid synthesis defects (4)

Trials to join now! 2 Not yet finished but already full! 1 Completed 1

Could a common cholesterol drug ease chronic diarrhoea?

Symptom relief Ongoing

This study tests whether atorvastatin, a drug typically used for cholesterol, can reduce bile acid production and improve symptoms in people with bile acid diarrhoea (BAD). Twenty adults with moderate-to-severe BAD will receive atorvastatin and a placebo in random order, each for…

Phase 4 • Sponsor: Asger Lund, MD • Aim: Symptom relief

Last updated Aug 13, 2026 00:00 UTC

Idiopathic malabsorption due to bile acid synthesis defects

Where it sits in the disease tree

Could a common cholesterol drug ease chronic diarrhoea?