Idiopathic hypercalciuria
MONDO:0700418A rare renal disease characterized by persistent excess urinary calcium excretion in the absence of an underlying systemic disease and hypercalcemia. The condition leads to an increased risk for the formation of kidney stones and nephrocalcinosis, as well as reduced bone mineral density with increased incidence of fractures in some patients.
3 clinical trials for this condition and its sub-types, 3 tagged with Idiopathic hypercalciuria itself.
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Common antibiotic could tame rare calcium disorder
Disease control Recruiting nowThis study tests whether the antibiotic rifampin can safely lower high calcium levels in the blood and urine of people with a rare genetic mutation in the CYP24A1 gene. The condition can cause kidney stones and other problems. Sixty participants aged 6 months to 65 years will tak…
Phase 2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Phosphate therapy's hidden toll on aging bodies revealed
Knowledge-focused Recruiting nowThis study looks at how long-term phosphate therapy affects the kidneys, blood vessels, and heart in people with two rare bone disorders: X-linked hypophosphatemia (XLH) and hereditary hypophosphatemic rickets with hypercalciuria (HHRH). Researchers will measure hormone levels an…
Early phase 1 • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC