IDH-wildtype anaplastic astrocytoma
MONDO:0850333An anaplastic astrocytoma lacking mutations in IDH1 or IDH2 genes.
2823 clinical trials for this condition and its sub-types, 3 tagged with IDH-wildtype anaplastic astrocytoma itself.
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New combo therapy targets aggressive brain tumors in phase 2 trial
Disease control Recruiting nowThis study tests a more intense treatment for a fast-growing type of brain cancer called IDH wildtype glioma. It combines higher doses of radiation with the chemotherapy drug temozolomide to try to stop the tumor from growing longer. The trial will enroll 40 adults with this spec…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Cold virus hijacked to attack returning brain tumors in early trial
Disease control Recruiting nowThis early-phase trial tests a modified cold virus (DNX-2401) that is loaded into donor stem cells and injected into the brain's blood supply to target recurrent high-grade gliomas. The virus is designed to infect and kill cancer cells while leaving healthy cells alone. The study…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC