Hypoplastic left heart syndrome
MONDO:0004933Hypoplastic left heart syndrome (HLHS) refers to the abnormal development of the left-sided cardiac structures, resulting in obstruction to blood flow from the left ventricular outflow tract. In addition, the syndrome includes underdevelopment of the left ventricle, aorta, and aortic arch, as well as mitral atresia or stenosis.
Also known as: HLHS
82 clinical trials for this condition and its sub-types, 9 tagged with Hypoplastic left heart syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Hypoplastic left heart syndrome
-
Hypoplastic left heart syndrome 1 0 trials
-
Hypoplastic left heart syndrome 2 0 trials
-
Fetal heart surgery could change life for babies with Half-Formed hearts
Disease control By invitation onlyThis study looks at a procedure done before birth to help babies with a severe heart defect called hypoplastic left heart syndrome (HLHS). The goal is to improve blood flow through the heart so that the baby may have a better chance at a two-sided heart repair after birth. The st…
Sponsor: Mauro H. Schenone • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
-
New app aims to ease Parents' stress over Baby's heart surgery decision
Symptom relief OngoingThis study tests whether a web-based decision aid app can reduce stress and improve decision-making for parents whose baby is diagnosed with a life-threatening congenital heart defect. 135 parents are randomly assigned to use the app alone or with an added values clarification ex…
Sponsor: University of Utah • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
-
Blood protein test could predict Post-Surgery risks in kids with heart defects
Knowledge-focused By invitation onlyThis study at Boston Children's Hospital will test whether measuring thousands of proteins in a few drops of blood can predict which children with congenital heart disease will have serious complications after heart surgery. Researchers will collect blood samples from 60 children…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
-
Heart defect study tracks kids' outcomes 11 years after surgery
Knowledge-focused OngoingThis study looks at 237 children born with hypoplastic left heart syndrome (HLHS), a serious heart defect. Researchers compare how well the heart works at age 11 in children who received one of two different shunts during their first surgery. The goal is to understand which shunt…
Sponsor: Carelon Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC