Hypophosphatasia
MONDO:0018570Hypophosphatasia (HPP) is a rare heritable metabolic disorder characterized by defective mineralization of bone and/or teeth in the presence of reduced activity of unfractionated serum alkaline phosphatase (ALP). The clinical spectrum is extremely wide, from stillbirth at one end to fractures of the lower extremities in adulthood, at the other, or even no bone manifestations (odontohypophosphatasia).
Also known as: HPP, Rathburn disease, deficiency of alkaline phosphatase (disorder) [ambiguous], phosphoethanolaminuria, childhood hypophosphatasia, hypophospatasia, childhood, hypophosphatasia mild, phosphoethanol-aminuria
13 clinical trials for this condition and its sub-types, 13 tagged with Hypophosphatasia itself.
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Browse by category →Sub-types of Hypophosphatasia
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1 sub-type
- Mild hypophosphatasia 0 trials
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2 sub-types
- Perinatal lethal hypophosphatasia 0 trials
- Severe hypophosphatasia 0 trials
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Adult hypophosphatasia 0 trials
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Childhood hypophosphatasia 0 trials
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Infantile hypophosphatasia 0 trials
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Moderate hypophosphatasia 0 trials
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Odontohypophosphatasia 0 trials
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Prenatal benign hypophosphatasia 0 trials