Hyperimmunoglobulinemia D with periodic fever
MONDO:0009849Hyperimmunoglobinemia D with periodic fever (HIDS) is a rare autoinflammatory disease characterized by periodic attacks of fever and a systemic inflammatory reaction (cervical lymphadenopathy, abdominal pain, vomiting, diarrhea, arthralgias and skin signs).
Also known as: HIDS, hyper-IgD syndrome, hyperimmunoglobinemia D with recurrent fever, hyperimmunoglobulinemia D syndrome, partial mevalonate kinase deficiency, hyper IgD syndrome, hyperimmunoglobulinemia D and periodic fever syndrome, periodic fever Dutch type
12 clinical trials for this condition and its sub-types, 2 tagged with Hyperimmunoglobulinemia D with periodic fever itself.
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Real-world check: does ilaris work safely for rare fever diseases?
Disease control Recruiting nowThis study watches children and adults who are already taking or about to start Ilaris for hereditary periodic fever syndromes or systemic juvenile idiopathic arthritis. Researchers will track side effects and how well the drug controls symptoms over 16 weeks. No new medicine is …
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Scientists seek genetic clues to mysterious fever diseases
Knowledge-focused Recruiting nowThis study aims to learn more about the genetics and natural history of autoinflammatory diseases, which cause repeated fevers and inflammation. Researchers will study up to 5,000 people, including patients, their relatives, and healthy volunteers. Participants provide blood and …
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Sep 11, 2026 00:00 UTC