Human infection by orthopoxvirus
MONDO:00185838 clinical trials for this condition and its sub-types, 5 tagged with Human infection by orthopoxvirus itself.
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New mRNA vaccine against mpox enters key trial in africa
Vaccine Recruiting nowThis study tests an experimental mRNA vaccine called BNT166a to see if it is safe and can protect against mpox (monkeypox). About 310 healthy adults in Africa will receive either the vaccine or a placebo. The trial is double-blind, meaning neither participants nor doctors know wh…
Phase 2 • Sponsor: BioNTech SE • Aim: Vaccine
Last updated Aug 13, 2026 00:00 UTC
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Experimental drug targets smallpox and monkeypox after exposure
Disease control Expanded accessThis trial tests the drug tecovirimat in people who have been exposed to or infected with orthopox viruses, including smallpox, monkeypox, and cowpox. Participants receive oral tecovirimat to see if it can control the infection and prevent serious complications. The study include…
Sponsor: U.S. Army Medical Research and Development Command • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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New poxvirus drug candidate tested in healthy people
Knowledge-focused Recruiting nowThis early-stage study tests the safety and how the body processes a new drug called BSY001 in 76 healthy adults aged 18 to 50. Participants receive either the drug or a placebo, and researchers monitor side effects and drug levels in the blood. The goal is to gather safety infor…
Phase 1 • Sponsor: China National Biotec Group Company Limited • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC