Hepatitis D virus infection
MONDO:0005789Inflammation of the liver in humans caused by hepatitis delta virus, a defective RNA virus that can only infect hepatitis B patients. For its viral coating, hepatitis delta virus requires the hepatitis B surface antigens produced by these patients. Hepatitis D can occur either concomitantly with (coinfection) or subsequent to (superinfection) hepatitis B infection. Similar to hepatitis B, it is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
Also known as: HDV, Hepatitis D, Hepatitis D virus, Hepatitis delta virus caused hepatitis, Hepatitis delta virus hepatitis, hepatitis delta, hepatitis type D
53 clinical trials for this condition and its sub-types, 47 tagged with Hepatitis D virus infection itself.
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Can a daily pill tame hepatitis d?
Disease control Not yet recruitingThis Phase 2 trial is testing an experimental oral drug called ABI-6250 in about 80 people with chronic hepatitis D, a serious liver infection. Participants take the pill once daily for 48 weeks. The study aims to see if the drug is safe, how it moves through the body, and whethe…
Phase 2 • Sponsor: Assembly Biosciences • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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New hope for hepatitis d: experimental drug enters final testing phase
Disease control Not yet recruitingThis Phase 3 trial tests a drug called hepalatide (L47) in 150 people with chronic hepatitis D, a serious liver disease. Participants receive either the drug or a placebo daily for 48 weeks. The goal is to see if hepalatide can lower virus levels and normalize liver enzymes. Afte…
Phase 3 • Sponsor: Shanghai HEP Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Can better surveillance of hepatitis b and d prevent liver damage?
Knowledge-focused Not yet recruitingThis observational study follows adults in France who are newly diagnosed with chronic hepatitis B (with or without hepatitis D). Researchers will measure liver scarring, treatment eligibility, and viral characteristics to understand how severe the disease is at diagnosis. The go…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC
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Massive french study to track virus effects on pregnant women and kids for 7 years
Knowledge-focused Not yet recruitingThis study will follow 5,160 pregnant women in France who have HIV, hepatitis B, hepatitis C, or an arbovirus infection (like Zika or dengue), along with their children, for up to 7 years. Researchers want to learn how these viruses and their treatments affect pregnancy, the moth…
Sponsor: ANRS, Emerging Infectious Diseases • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New study aims to unlock secrets of hepatitis d treatment success
Knowledge-focused Not yet recruitingThis observational study looks at data and samples from 220 people with hepatitis D (HDV) who are already taking the medication bulevirtide. Researchers want to see how well the drug works over time and find markers that predict a good response. The goal is to improve monitoring …
Sponsor: University of Rome Tor Vergata • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC