Hand-foot syndrome
MONDO:0700048A condition characterized by redness, pain, swelling, and tingling in the palms of the hands or the soles of the feet. It may appear as a side effect to chemotherapy agents.
Also known as: palmar-plantar erythrodysthesia
9 clinical trials for this condition and its sub-types, 9 tagged with Hand-foot syndrome itself.
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New gel aims to stop chemo side effect that makes hands hurt
Prevention Not yet recruitingThis study tests a gel called TAR-0520 to see if it can prevent hand-foot syndrome, a painful skin reaction caused by the chemotherapy drug capecitabine. About 25 people with breast or colorectal cancer will apply the gel to their hands twice daily for 12 weeks. Their feet will n…
Phase 2 • Sponsor: Tarian Pharma • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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New plaster aims to soothe chemo side effect
Symptom relief Not yet recruitingThis study tests whether a plaster containing uracil can reduce symptoms of hand-foot syndrome (HFS) in adults undergoing chemotherapy. HFS causes redness, swelling, and pain on the hands and feet. Researchers will compare the uracil plaster to a standard soothing cream. About 80…
Sponsor: Wooshin Labottach Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Herbal soak may soothe Chemo's painful side effects
Symptom relief Not yet recruitingThis study tests whether a traditional Chinese medicine hand-foot soak can reduce nerve pain and skin reactions caused by chemotherapy. About 300 adults with solid tumors who have these side effects will use the soak. The goal is to see if it improves symptoms and quality of life…
Sponsor: Peking University Third Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC