Hairy cell leukemia
MONDO:0018935Hairy cell leukemia (HCL) is a rare type of leukemia in which abnormal B-lymphocytes are present in the bone marrow, spleen and peripheral blood. It is a slowly progressive chronic lymphocytic leukemia (CLL). The name comes from the abnormally shaped lymphocytes with hair-like projections.
Also known as: HCL, HCL-C, hairy cell leukemia, leukemic reticuloendotheliosis, classic hairy cell leukaemia, classic hairy cell leukemia
2065 clinical trials for this condition and its sub-types, 40 tagged with Hairy cell leukemia itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hairy cell leukemia
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Hairy cell leukemia variant 9 trials
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Refractory hairy cell leukemia 9 trials
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Ready-Made immune cells take on blood cancers in early trial
Disease control Not yet recruitingThis early-phase study tests a new cell therapy called ALA-101 for people with CD19+ non-Hodgkin lymphoma or leukemia. The therapy uses donor immune cells that are specially designed to find and attack cancer cells. The main goals are to check safety and find the best dose, with …
Phase 1 • Sponsor: Arovella Therapeutics Ltd • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Engineered immune cells take aim at stubborn blood cancers
Disease control Not yet recruitingThis phase 1 trial is testing a new kind of CAR-T cell therapy, called LMY-922, for people with certain blood cancers that have not responded to standard treatments. The therapy uses donor immune cells engineered to target a protein called BAFF on cancer cells. The study aims to …
Phase 1 • Sponsor: Luminary Therapeutics • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Can 3D-Printed models unlock personalized blood cancer therapies?
Knowledge-focused Not yet recruitingThis study aims to create 3D models of B-cell cancers—like chronic lymphocytic leukemia, splenic marginal-zone lymphoma, and hairy cell leukemia—using blood samples from patients. The goal is to build realistic models that mimic the tumor environment, which could help researchers…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC