Granular cell tumor
MONDO:0006235An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast.
Also known as: Abrikossoff tumor, Abrikossoff tumour, Abrikossoff's tumor, Abrikossoff's tumour, granular cell myoblastoma, granular cell neoplasm, granular cell nerve sheath tumor, granular cell nerve sheath tumour
1447 clinical trials for this condition and its sub-types, 2 tagged with Granular cell tumor itself.
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Sub-types of Granular cell tumor
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Granular cell cancer 1 trial · 2 incl. sub-types
4 sub-types
- Malignant cutaneous granular cell skin tumor 1 trial
- Granular cell carcinoma 0 trials
- Granular cell leiomyosarcoma 0 trials
- Malignant gastric granular cell tumor 0 trials
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Cutaneous granular cell tumor 0 trials · 1 incl. sub-types
1 sub-type
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Benign granular cell tumor 0 trials
2 sub-types
- Benign peripheral nerve granular cell tumor 0 trials
- Cardiac granular cell neoplasm 0 trials
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Breast granular cell tumor 0 trials
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Congenital epulis 0 trials
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Esophageal granular cell tumor 0 trials
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Neurohypophysis granular cell tumor 0 trials
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Vulvar granular cell tumor 0 trials
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New hope for rare childhood cancer: drug cocktail aims to shrink tumors and prevent return
Disease control Recruiting nowThis study is for children and young adults (up to age 30) with a rare type of soft tissue cancer called non-rhabdomyosarcoma. It tests whether adding the drugs pazopanib and selinexor to standard chemotherapy can improve outcomes. Participants receive treatment tailored to their…
Phase 1/2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New chemo cocktail aims to tackle rare brain tumors
Disease control Recruiting nowThis phase 2 trial is testing a combination of two chemotherapy drugs, teniposide and cisplatin, in 40 people newly diagnosed with central malignant germ cell tumors. The goal is to see if the combo is safe and effective at shrinking tumors and prolonging survival. Researchers wi…
Phase 2 • Sponsor: Chengcheng Guo • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC