Gliosarcoma

MONDO:0016681

A rare histological variant of glioblastoma (WHO grade IV) characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation (WHO).

Also known as: glioblastoma with a sarcomatous component, gliosarcoma, sarcomatous glioblastoma

2946 clinical trials for this condition and its sub-types, 65 tagged with Gliosarcoma itself.

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Where it sits in the disease tree

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Part of

↑ Brain glioblastoma (87)

Including sub-types (2946) Tagged with Gliosarcoma (65)

Trials to join now! 23 Not yet recruiting 1 Not yet finished but already full! 23 Completed 13 Terminated 5

Radioactive antibody and immunotherapy combo targets recurrent brain cancer

Disease control Not yet recruiting

This early-phase trial tests a new combination for recurrent glioblastoma, a fast-growing brain tumor. The treatment pairs Actimab-A, a radioactive antibody that seeks out cancer cells, with cemiplimab, an immunotherapy that helps the immune system attack tumors. About 30 adults …

Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control

Last updated Jun 27, 2026 13:06 UTC

Gliosarcoma

Where it sits in the disease tree

Radioactive antibody and immunotherapy combo targets recurrent brain cancer