Giant cell tumor of soft tissue

MONDO:0006232

A painless, well circumscribed tumor arising in soft tissue, usually of the upper and lower extremities. Morphologically, it is characterized by a multinodular growth pattern. The cellular infiltrate is composed of mononuclear round or oval cells and multinucleated osteoclast-like giant cells, in a rich vascular stroma. It rarely metastasizes.

Also known as: GCT-ST, Osteoclastoma of soft tissue, giant cell tumor of soft tissue

2775 clinical trials for this condition and its sub-types, 1 tagged with Giant cell tumor of soft tissue itself.

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↑ Sarcoma (1028) ↑ Malignant giant cell tumor (4)

Including sub-types (2775) Tagged with Giant cell tumor of soft tissue (1)

Trials to join now! 1

New hope for rare childhood cancer: drug cocktail aims to shrink tumors and prevent return

Disease control Recruiting now

This study is for children and young adults (up to age 30) with a rare type of soft tissue cancer called non-rhabdomyosarcoma. It tests whether adding the drugs pazopanib and selinexor to standard chemotherapy can improve outcomes. Participants receive treatment tailored to their…

Phase 1/2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control

Last updated Aug 05, 2026 00:00 UTC

Giant cell tumor of soft tissue

Where it sits in the disease tree

New hope for rare childhood cancer: drug cocktail aims to shrink tumors and prevent return