Giant cell glioblastoma
MONDO:0016682A rare histological variant of glioblastoma (WHO grade IV) with a predominance of bizarre, multinucleated giant cells, an occasionally abundant stromal reticulin network, and a high frequency of TP53 mutations. (WHO)
Also known as: Monstrocellular sarcoma [obs]
2901 clinical trials for this condition and its sub-types, 7 tagged with Giant cell glioblastoma itself.
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Second radiation blast shows promise for tough brain cancer
Disease control CompletedThis study tested giving a second round of radiation to people whose glioblastoma (a fast-growing brain tumor) came back after standard treatment. Seventeen adults aged 18 to 50 received daily radiation for 2-3 weeks. The goal was to find the safest highest dose and see how it af…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New brain scan could sharpen surgery for glioma patients
Knowledge-focused CompletedThis pilot study tested whether a special PET scan using 18F-FDOPA can help doctors better plan surgery and radiation for people with newly diagnosed brain tumors (gliomas). Twenty-four adults took part at Mayo Clinic. The goal was to see if the scan provides useful information b…
Early phase 1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:06 UTC