Giant axonal neuropathy 2
MONDO:0012411Any giant axonal neuropathy in which the cause of the disease is a mutation in the DCAF8 gene.
Also known as: CMT2 with giant axons, DCAF8 giant axonal neuropathy, HMSN2 with giant axons, autosomal dominant hereditary motor and sensory neuropathy type 2 with giant axons, giant axonal neuropathy caused by mutation in DCAF8, giant axonal neuropathy type 2, GAN2, autosomal dominant Charcot-Marie-Tooth disease type 2 with giant axons
9 clinical trials for this condition and its sub-types, 0 tagged with Giant axonal neuropathy 2 itself.
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Wearable gadget aims to stop falls in neuropathy patients
Symptom relief Recruiting nowThis study tests a device called Walkasins, worn on the lower legs, that vibrates to give sensory feedback about foot pressure. The goal is to see if using it daily for six months improves balance and walking in 200 adults aged 55+ with peripheral neuropathy. Participants will do…
Sponsor: RxFunction Inc. • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Global registry aims to map the full course of Charcot-Marie-Tooth disease
Knowledge-focused Recruiting nowResearchers are building a global registry to collect patient-reported surveys, genetic test results, and medical records from people with Charcot-Marie-Tooth disease and related inherited neuropathies. The study is open to children and adults with a confirmed or suspected diagno…
Sponsor: Hereditary Neuropathy Foundation • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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Massive study seeks answers for rare inherited nerve diseases
Knowledge-focused Recruiting nowThis study aims to learn more about rare inherited disorders that affect the brain, spinal cord, muscles, and nerves. Researchers will collect medical history, perform exams, and run genetic tests on up to 3,500 participants. No new treatments are tested; the goal is to better un…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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4,000 patients to help unlock secrets of nerve disease
Knowledge-focused Recruiting nowThis study is collecting information from 4,000 adults with peripheral neuropathy (nerve damage) to better understand the condition. Researchers will combine standard tests with nerve ultrasound to see if it helps diagnose and track the disease. No new treatments are being tested…
Sponsor: Casa di Cura Dott. Pederzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Liquid nerve biopsy could unlock ALS secrets
Knowledge-focused Recruiting nowThis study is collecting nerve samples and biofluids from 400 people with ALS or peripheral neuropathies to find biological markers for early diagnosis and disease tracking. By analyzing individual cells, researchers hope to identify molecular changes that happen before symptoms …
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Massive CMT study aims to map disease progression over five years
Knowledge-focused Recruiting nowThis observational study follows up to 5,000 people with Charcot Marie Tooth disease (CMT) types 1B, 2A, 4A, and 4C over five years. Researchers will measure symptoms, nerve function, and disability using special scales to understand how the disease changes over time. The goal is…
Sponsor: Michael Shy • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Scientists hunt for hidden genes behind nerve disease severity
Knowledge-focused Recruiting nowThis study aims to find new genes that cause Charcot-Marie-Tooth disease (CMT) and discover why symptoms differ among people with the same genetic change. Researchers will analyze DNA from up to 1,050 participants to identify genetic modifiers and unknown causes. The goal is to b…
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC