Germinoma
MONDO:0002598A malignant germ cell tumor arising in the central nervous system. It is characterized by the presence of primitive, large malignant germ cells and lymphocytes.
Also known as: germinoma, germinoma (disease)
2742 clinical trials for this condition and its sub-types, 7 tagged with Germinoma itself.
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Sub-types of Germinoma
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Extragonadal germinoma 0 trials · 4 incl. sub-types
1 sub-type
- Central nervous system germinoma 2 trials · 4 incl. sub-types Sub-types →
Most studied deeper sub-types
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Immunotherapy duo takes on resistant germ cell tumors
Disease control OngoingThis phase 2 trial tests two immunotherapy drugs, durvalumab and tremelimumab, in 30 adults with relapsed or refractory germ cell tumors. The goal is to see if the combination can shrink tumors or lower tumor markers. Participants must have measurable disease and have progressed …
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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High-Dose chemo with stem cell transplant tested against standard therapy for tough germ cell cancers
Disease control OngoingThis phase 3 trial compares two chemotherapy approaches for people with germ cell tumors that have returned or not responded to initial treatment. One group receives standard-dose chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP). The other receives high-dose chemothe…
Phase 3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC