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Generalized lipodystrophy

MONDO:0027766

Almost complete absence of subcutaneous and/or visceral adipose tissue.

Also known as: complete generalised lipodystrophy, complete generalized lipodystrophy

12 clinical trials for this condition and its sub-types, 8 tagged with Generalized lipodystrophy itself.

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Where it sits in the disease tree

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Part of

↑ Lipodystrophy (48)

Sub-types of Generalized lipodystrophy

Congenital generalized lipodystrophy 2 trials · 3 incl. sub-types
5 sub-types
- Congenital generalized lipodystrophy type 3 1 trial
- Congenital generalized lipodystrophy type 1 0 trials
- Congenital generalized lipodystrophy type 2 0 trials
- Congenital generalized lipodystrophy type 4 0 trials
- Lipodystrophy, congenital generalized, type 5 0 trials
Acquired generalized lipodystrophy 0 trials

Including sub-types (12) Tagged with Generalized lipodystrophy (8)

Trials to join now! 3 Not yet finished but already full! 1 Completed 3 Terminated 1

Lifesaving drug made available for rare fat disorder patients

Disease control Ongoing

This study gives the drug metreleptin to people with generalized lipodystrophy, a rare condition that causes severe fat loss and leads to high blood fats and diabetes. Participants, aged 6 months and older, have already received metreleptin in past NIH studies but cannot get it i…

Phase 3 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control

Last updated Sep 18, 2026 00:00 UTC