Gastric mucosa-associated lymphoid tissue lymphoma

MONDO:0006226

A low grade, indolent B-cell lymphoma, usually associated with Helicobacter pylori infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic (centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy.

Also known as: MALT lymphoma of stomach, MALT lymphoma of the stomach, MALToma of stomach, MALToma of the stomach, gastric MALT lymphoma, gastric MALToma, gastric mucosa-associated lymphoid tissue lymphoma, primary MALT lymphoma of stomach

3305 clinical trials for this condition and its sub-types, 2 tagged with Gastric mucosa-associated lymphoid tissue lymphoma itself.

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Where it sits in the disease tree

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↑ MALT lymphoma (31) ↑ Hereditary gastric cancer (6) ↑ Gastric non-hodgkin lymphoma (2) ↑ Spleen cancer (2)

Including sub-types (3305) Tagged with Gastric mucosa-associated lymphoid tissue lymphoma (2)

Not yet recruiting 1 Not yet finished but already full! 1

New drug duo targets hard-to-treat lymphoma

Disease control Not yet recruiting

This study tests a combination of two drugs, nemtabrutinib and rituximab, in about 35 adults with marginal zone lymphoma, a slow-growing blood cancer. The goal is to see if the combo is safe and can shrink or eliminate tumors. Participants will receive the drugs by mouth and thro…

Phase 2 • Sponsor: City of Hope Medical Center • Aim: Disease control

Last updated Jun 27, 2026 12:33 UTC

Gastric mucosa-associated lymphoid tissue lymphoma

Where it sits in the disease tree

New drug duo targets hard-to-treat lymphoma