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Fibrous dysplasia
MONDO:0000845A genetic, non-inheritable disorder caused by osteoblastic differentiation defects that result in the replacement of bone marrow and trabecular bone by fibrous stroma and immature bone. It usually affects a single bone and less frequently multiple bones. Skull, femur, tibia, and humerus are the most frequently affected bones. It manifests with pain, deformities, and fractures.
Also known as: fibrous dysplasia of bone
11 clinical trials for this condition and its sub-types, 11 tagged with Fibrous dysplasia itself.
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Sub-types of Fibrous dysplasia
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Polyostotic fibrous dysplasia 8 trials
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Monostotic fibrous dysplasia 0 trials
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Panostotic fibrous dysplasia 0 trials
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Custom 3D-Printed titanium implants could rebuild faces after injury or surgery
Disease control Recruiting nowThis study tests whether custom 3D-printed titanium implants can safely and effectively rebuild facial bones in 30 adults with defects from injury, cancer surgery, or birth conditions. Each implant is designed from CT scans to match the patient's unique anatomy. Researchers will …
Sponsor: Tishreen University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Scientists launch major study to unravel rare bone disease
Knowledge-focused Recruiting nowThis study follows up to 500 people with polyostotic fibrous dysplasia or McCune-Albright syndrome to learn how these conditions change over time. Researchers will collect medical data and tissue samples to better understand the disease. The goal is to improve future diagnosis an…
Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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200-Patient study aims to unlock secrets of rare bone disease
Knowledge-focused Recruiting nowThis study looks back at the medical records of over 200 people with fibrous dysplasia, a rare bone condition that causes abnormal growths. Researchers want to learn more about the disease's features, treatments, and genetic causes. No new treatments are being tested; the goal is…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC