Fetal alcohol syndrome
MONDO:0016011Fetal alcohol syndrome (FAS) is a rare malformation syndrome caused by excessive maternal consumption of alcohol during pregnancy. It is characterized by prenatal and/or postnatal growth deficiency (weight and/or height <10th percentile), a unique cluster of minor facial anomalies (short palpebral fissures, flat and smooth philtrum, and thin upper lip) and severe central nervous system (CNS) abnormalities including microcephaly, and cognitive and behavioral impairment (intellectual disability, deficit in general cognition, learning and language, executive function, visual-spatial processing, memory, and attention).
Also known as: FASD, fetal alcohol spectrum disorders, foetal alcohol spectrum disorders, ARBD, ARND, FAS, alcohol-related neurodevelopmental disorder, alcohol-related birth defects
117 clinical trials for this condition and its sub-types, 17 tagged with Fetal alcohol syndrome itself.
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Can a smartphone app curb drinking during pregnancy?
Disease control CompletedThis study tested a phone-based program called MommyCheckup to see if it helps pregnant women who drink alcohol cut back or stop. The program includes a short motivational video and tailored text messages. Researchers enrolled 384 pregnant women across three states to see if the …
Sponsor: Michigan State University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New app aims to ease parenting challenges for kids with FASD
Symptom relief CompletedThis study tested a smartphone app called FMF Connect for parents and caregivers of children with fetal alcohol spectrum disorders (FASD). The app provides helpful information and peer support to manage children's behavior. 129 parents participated, and researchers measured chang…
Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Green tea extract may sharpen minds of kids with fetal alcohol syndrome
Symptom relief CompletedThis pilot study tested whether a daily dose of EGCG, a natural compound found in green tea, could improve cognitive performance in 36 children aged 7 to 14 with fetal alcohol syndrome. The children took EGCG for one year and had their thinking skills measured at the start, at 6 …
Sponsor: Fundacion Clinic per a la Recerca Biomédica • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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A drop of blood may reveal hidden prenatal alcohol exposure
Knowledge-focused CompletedThis study is testing whether epigenetic changes in newborn blood can serve as a biomarker for fetal alcohol spectrum disorder (FASD). Researchers will collect umbilical cord blood at birth and heel stick blood at 48 hours from 600 newborns, and compare these with blood alcohol l…
Sponsor: CAMC Health System • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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Scientists hunt for genetic fingerprints to detect FASD earlier
Knowledge-focused CompletedThis study looked at 188 children (ages 0-18) with Fetal Alcohol Spectrum Disorders (FASD) in Reunion Island to better describe the condition and find a unique "epigenetic signature" in their DNA. Researchers collected blood and cheek swabs from a small group of children with FAS…
Sponsor: Centre Hospitalier Universitaire de la Réunion • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC