Familial ovarian carcinoma
MONDO:0100514Ovarian carcinoma that has developed in relatives of patients that have a history of ovarian carcinoma.
Also known as: hereditary ovarian cancer, familial ovarian carcinoma, hereditary ovarian carcinoma, familiar ovarian carcinoma
2855 clinical trials for this condition and its sub-types, 5 tagged with Familial ovarian carcinoma itself.
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New drug combo targets BRCA cancers in early trial
Disease control OngoingThis early-phase study tests a combination of two drugs, niraparib and dostarlimab, in 18 adults with BRCA-mutated breast, pancreas, or ovary cancer that has spread or cannot be surgically removed. Niraparib blocks a DNA repair protein in cancer cells, while dostarlimab helps the…
Phase 1 • Sponsor: University of Washington • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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Weight loss program aims to cut cancer risk in BRCA and lynch syndrome carriers
Disease control OngoingThis study tests a weight management and health behavior program for people with BRCA or Lynch syndrome mutations, who have a higher risk of certain cancers. Participants receive diet tracking, exercise guidance, phone coaching, and online support to help them lose weight and ado…
Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Phone counseling helps latinas navigate cancer risk
Knowledge-focused OngoingThis study tests whether a culturally-informed telephone counseling program can help Latina women at high risk for hereditary breast or ovarian cancer learn more about their risk and feel more in control. About 493 women with a personal or family history of these cancers will tak…
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC