Familial adenomatous polyposis 1

An autosomal dominant disorder caused by pathogenic variants in the APC gene, characterized by the development of colorectal adenomatous polyposis, a very high risk of colorectal cancer and other extracolonic manifestations including both classic and attenuated familial adenomatous polyposis (FAP).

Also known as: adenomatous polyposis coli, APC-related adenomatous polyposis, FAP1, adenoma, periampullary, somatic, familial adenomatous polyposis 1, Gardner syndrome, adenomatous polyposis coli, attenuated, adenomatous polyposis of the colon

36 clinical trials for this condition and its sub-types, 2 tagged with Familial adenomatous polyposis 1 itself.