Extramedullary plasmacytoma
MONDO:0002754A plasma cell neoplasm arising at an extraosseous site. There is no involvement of the bone marrow. It most frequently involves the oropharynx, nasopharynx, sinuses, and larynx. Other sites of involvement include the gastrointestinal tract, central nervous system, breast, skin, lymph nodes, and bladder. A minority of patients have a monoclonal gammopathy. Treatment includes radiation therapy. Progression to plasma cell myeloma occurs in a minority of patients.
Also known as: extramedullary plasmacytoma, extramedullary plasmacytoma (clinical), extraosseous plasmacytoma, plasmacytoma, extramedullary, plasmacytoma, extramedullary (not occurring in bone), EP
1935 clinical trials for this condition and its sub-types, 7 tagged with Extramedullary plasmacytoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
-
Experimental CAR-T therapy targets tough blood cancers in early trial
Disease control Not yet recruitingThis early-phase trial tests a new type of immune cell therapy called GPRC5D CAR-T in 18 people with relapsed or treatment-resistant plasma cell disorders, such as multiple myeloma. The therapy involves giving patients a single infusion of their own modified immune cells designed…
Early phase 1 • Sponsor: Qi deng • Aim: Disease control
Last updated Jun 27, 2026 08:15 UTC
-
Scientists hunt for clues in archived myeloma samples
Knowledge-focused Not yet recruitingThis study will check if old tissue samples from 15 patients with extramedullary multiple myeloma can be used to find new biomarkers. Researchers will look at the samples and medical records to see if they are good enough for future research. No new treatments or tests are given—…
Sponsor: BIWAKO • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC