Esophageal melanoma

MONDO:0001192

A melanoma affecting the esophageal wall. Melanoma in the esophagus is more commonly metastatic than primary. Primary melanomas of the esophagus are polypoid and clinically aggressive. (WHO, 2000)

Also known as: esophageal melanoma, esophagus melanoma, esophagus melanoma (disease), melanoma (disease) of esophagus, melanoma (disease) of oesophagus, melanoma of esophagus, melanoma of oesophagus, melanoma of the esophagus

2866 clinical trials for this condition and its sub-types, 1 tagged with Esophageal melanoma itself.

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Where it sits in the disease tree

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Part of

↑ Esophageal cancer (791) ↑ Digestive system melanoma (2)

Including sub-types (2866) Tagged with Esophageal melanoma (1)

Not yet finished but already full! 1

New drug cocktail aims to prevent rare melanoma recurrence

Disease control Ongoing

This phase II trial tests whether adding cabozantinib to the immunotherapy drug nivolumab can prevent mucosal melanoma from returning after surgery. About 101 patients with resected mucosal melanoma will receive either nivolumab alone or nivolumab plus cabozantinib. The study aim…

Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control

Last updated Aug 06, 2026 00:00 UTC

Esophageal melanoma

Where it sits in the disease tree

New drug cocktail aims to prevent rare melanoma recurrence