Please sign in to follow a disease.
Erythroplakia
MONDO:0023089A clinical term that refers to the presence of a red flat and well defined lesion on the oral mucosa that is not caused by trauma, vascular, or inflammatory processes. It is a precancerous condition and is seen more commonly in middle aged or older males. It is associated with tobacco and alcohol consumption. Microscopic examination reveals severe epithelial dysplasia, carcinoma in situ, or invasive squamous cell carcinoma.
Also known as: erythroplakia
1434 clinical trials for this condition and its sub-types, 8 tagged with Erythroplakia itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
-
Immunotherapy tackles precancerous mouth spots
Disease control Recruiting nowThis trial tests whether pembrolizumab (Keytruda), an immunotherapy drug that helps the immune system attack abnormal cells, can shrink or control leukoplakia—a precancerous condition of the mouth. The study includes people with leukoplakia or related lesions that cannot be remov…
Phase 2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
-
New imaging tool could make mouth biopsies more accurate
Diagnosis Recruiting nowThis study tests a new imaging device called the Active Biopsy Guidance System to help doctors decide when and where to take tissue samples (biopsies) from mouth lesions. About 90 adults with suspicious mouth spots or a history of oral cancer will participate. The goal is to see …
Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Aug 12, 2026 00:00 UTC
-
New study aims to unlock secrets of oral cancer through tissue and symptom tracking
Knowledge-focused Recruiting nowThis study is for 1000 people with oral cancer or precancerous mouth lesions. Researchers will collect tissue samples and ask participants about their symptoms before, during, and after treatment. The goal is to find better ways to predict how the disease will behave and which tr…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC