Eosinophilic granuloma

A clinical variant of Langerhans cell histiocytosis characterized by unifocal involvement of a bone (most often), skin, or lung. Patients are usually older children or adults usually presenting with a lytic bone lesion. The etiology is unknown. Morphologically, eosinophilic granuloma is characterized by the presence of Langerhans cells in a characteristic milieu which includes histiocytes, eosinophils, neutrophils, and small, mature lymphocytes.

Also known as: Monostotic Langerhans cell histiocytosis, chronic and localised Langerhans cell histiocytosis, chronic and localized Langerhans cell histiocytosis, chronic unifocal Langerhans cell histiocytosis, eosinophilic granuloma, eosinophilic xanthomatous granuloma, unifocal Langerhans cell histiocytosis

1849 clinical trials for this condition and its sub-types, 0 tagged with Eosinophilic granuloma itself.