Embryonal neoplasm
MONDO:0005564A usually malignant neoplasm composed of primitive (immature) tissues that resemble fetal tissues. Medulloblastoma, Ependymoblastoma, Pineoblastoma, and Wilms tumor are representative embryonal neoplasms. --2003
Also known as: embryonal neoplasm, embryonal tumor, embryonal tumour, EMBT, embryonal cancer
1870 clinical trials for this condition and its sub-types, 9 tagged with Embryonal neoplasm itself.
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Sub-types of Embryonal neoplasm
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Primitive neuroectodermal tumor 14 trials · 228 incl. sub-types
5 sub-types
- Neuroblastic tumor 3 trials · 206 incl. sub-types Sub-types →
- Central nervous system primitive neuroectodermal neoplasm 8 trials · 24 incl. sub-types Sub-types →
- Peripheral primitive neuroectodermal tumor 7 trials · 8 incl. sub-types Sub-types →
- Melanotic neuroectodermal tumor 0 trials
- Primitive neuroectodermal tumor of the corpus uteri 0 trials
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Ewing sarcoma/peripheral primitive neuroectodermal tumor 7 trials · 149 incl. sub-types
5 sub-types
- Ewing sarcoma 124 trials · 125 incl. sub-types Sub-types →
- Central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor 1 trial · 22 incl. sub-types Sub-types →
- Peripheral primitive neuroectodermal tumor 7 trials · 8 incl. sub-types Sub-types →
- Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone 0 trials · 7 incl. sub-types Sub-types →
- Extraskeletal Ewing sarcoma/peripheral primitive neuroectodermal tumor 0 trials · 4 incl. sub-types Sub-types →
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Medulloblastoma 110 trials
14 sub-types
- Childhood medulloblastoma 14 trials
- Medulloblastoma non-WNT/non-SHH 1 trial · 4 incl. sub-types Sub-types →
- Medulloblastoma SHH activated 3 trials Sub-types →
- Anaplastic/large cell medulloblastoma 2 trials
- Adult medulloblastoma 1 trial
- Cerebellar vermis medulloblastoma 1 trial
- Medulloblastoma WNT activated 1 trial
- Brain stem medulloblastoma 0 trials
- Classic medulloblastoma 0 trials
- Desmoplastic/nodular medulloblastoma 0 trials
- Large cell medulloblastoma 0 trials
- Medulloblastoma with extensive nodularity 0 trials
- Medullomyoblastoma with myogenic differentiation 0 trials
- Melanotic medulloblastoma 0 trials
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Rhabdoid tumor 63 trials · 75 incl. sub-types
5 sub-types
- Atypical teratoid rhabdoid tumor 35 trials · 36 incl. sub-types Sub-types →
- Rhabdoid tumor of the kidney 7 trials
- Extrarenal rhabdoid tumor 1 trial
- Familial rhabdoid tumor 0 trials · 1 incl. sub-types Sub-types →
- Striated muscle rhabdoid tumor 0 trials
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Wilms tumor 60 trials · 63 incl. sub-types
4 sub-types
- Kidney Wilms tumor 9 trials · 11 incl. sub-types Sub-types →
- Hereditary Wilms tumor 1 trial · 5 incl. sub-types Sub-types →
- Cervical Wilms tumor 0 trials
- Ovarian Wilms tumor 0 trials
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Hepatoblastoma 42 trials
2 sub-types
- Macrotrabecular hepatoblastoma 0 trials
- Mixed hepatoblastoma 0 trials
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Notochordal tumor 0 trials · 34 incl. sub-types
1 sub-type
- Chordoma 30 trials · 34 incl. sub-types Sub-types →
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Pineoblastoma 15 trials
1 sub-type
- Adult pineoblastoma 0 trials
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Blastoma 0 trials · 4 incl. sub-types
3 sub-types
- Pulmonary blastoma 1 trial · 4 incl. sub-types Sub-types →
- Gonadoblastoma 0 trials Sub-types →
- Pituitary blastoma 0 trials
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Congenital mesoblastic nephroma 2 trials
2 sub-types
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Testicular embryonal carcinoma 1 trial · 2 incl. sub-types
2 sub-types
- Intratubular embryonal carcinoma 1 trial
- Childhood embryonal testis carcinoma 0 trials
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Intraocular medulloepithelioma 1 trial
Most studied deeper sub-types
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New antibody combo targets tough lymphoma in early trial
Disease control Recruiting nowThis study tests a new drug called EMB-07, which is a bispecific antibody that helps the immune system attack cancer cells. It is for people with aggressive B-cell non-Hodgkin lymphoma, either newly diagnosed or whose cancer has come back. The trial will check safety, side effect…
Phase 1/2 • Sponsor: Shanghai EpimAb Biotherapeutics Co., Ltd. • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Engineered t cells take on deadly brain cancers
Disease control Recruiting nowThis early-phase trial tests a new type of immune therapy for people with certain aggressive brain tumors, including DIPG and high-grade glioma. The treatment uses the patient's own T cells, which are modified in the lab to recognize a protein called GD2 on cancer cells and to pr…
Phase 1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Promising targeted therapy for tough brain cancers moves forward
Disease control Recruiting nowThis study is testing a drug called Lutathera in children and young adults (ages 4 to 39) whose brain tumors have come back or are growing despite treatment. The drug delivers radiation directly to tumor cells that show up on a special PET scan. The goal is to find the safest dos…
Phase 1/2 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Brain tumor virus therapy tested in kids and young adults
Disease control Recruiting nowThis phase 2 trial tests whether a single injection of DNX-2401, a virus designed to kill cancer cells, can shrink or stabilize recurrent high-grade brain tumors in 39 children and young adults. Participants receive the virus directly into the tumor during a biopsy procedure. The…
Phase 2 • Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Ultrasound 'Key' may let chemo reach Kids' brain tumors
Disease control Recruiting nowThis early-stage trial tests whether a device called SonoCloud-9 can safely open the blood-brain barrier in children aged 5 to 17 with recurrent malignant brain tumors. The barrier normally blocks chemotherapy from reaching the brain. By using low-intensity ultrasound just before…
Phase 1 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New hope for kids with tough brain tumors: gene therapy meets immunotherapy and radiation
Disease control Recruiting nowThis early-phase trial is testing a combination of three treatments for children whose brain tumors have come back or not responded to standard care. The experimental drug SGT-53 delivers a normal TP53 gene to tumor cells, and is given alongside the immunotherapy Nivolumab and ra…
Early phase 1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New brain tumor labels could guide better treatments
Knowledge-focused Recruiting nowThis study is collecting data from 1,650 people with various brain tumors to see if the updated 2021 WHO classification system helps doctors group patients more accurately and choose better treatments. Researchers will track responses to therapy, survival, and tumor features over…
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC