Eisenmenger syndrome
MONDO:0019944Eisenmenger syndrome (ES) is an form of pulmonary arterial hypertension (PAH) associated with unoperated congenital heart disease and is characterized by congenital heart malformations with reversed or bi-directional shunting through an intra-cardiac or intervascular (usually aorto-pulmonary) communication with the development of PAH.
Also known as: Eisenmenger's syndrome
26 clinical trials for this condition and its sub-types, 5 tagged with Eisenmenger syndrome itself.
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Small study aims to unlock secrets of rare lung disease
Knowledge-focused CompletedThis completed Phase 1 study looked at 27 people with and without pulmonary hypertension to learn more about how blood vessel problems contribute to the disease. Researchers used heart catheterization, imaging, and blood tests to find biomarkers and understand disease mechanisms.…
Phase 1 • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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New MRI scan could replace invasive heart test for lung pressure patients
Knowledge-focused CompletedThis study looked at whether a special MRI scan (4D Flow) can accurately measure blood flow to the lungs in people with both congenital heart disease and pulmonary hypertension. The standard test for this is a heart catheterization, which is invasive and uncomfortable. The study …
Sponsor: Centre Chirurgical Marie Lannelongue • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC