Eisenmenger syndrome
MONDO:0019944Eisenmenger syndrome (ES) is an form of pulmonary arterial hypertension (PAH) associated with unoperated congenital heart disease and is characterized by congenital heart malformations with reversed or bi-directional shunting through an intra-cardiac or intervascular (usually aorto-pulmonary) communication with the development of PAH.
Also known as: Eisenmenger's syndrome
26 clinical trials for this condition and its sub-types, 5 tagged with Eisenmenger syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
New ECMO technique aims to bridge lung transplant patients safely to surgery
Disease control Recruiting nowThis early-stage study tests a new way to use a heart-lung machine (ECMO) in 4 people waiting for a lung transplant who also have heart failure from high blood pressure in the lungs. The goal is to see if this approach can keep them alive and stable until they receive a transplan…
Phase 1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
-
New drug combo could help heart defect patients with severe lung pressure
Disease control Recruiting nowThis study tests whether adding the drug sotatercept to usual treatments can improve exercise ability in adults with pulmonary arterial hypertension (PAH) from unrepaired heart defects, including Eisenmenger syndrome. About 36 adults in Japan will be randomly assigned to receive …
Phase 4 • Sponsor: Kazuya Hosokawa • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC